发明名称 |
Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria |
摘要 |
The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out: a) Fermentation of microorganisms in which at least the thrE gene is amplified (overexpressed), optionally in combination with further genes, b) Enrichment of the L-threonine in the medium or in the cells of the microorganisms, and c) Isolation of the L-threonine.
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申请公布号 |
US2003049802(A1) |
申请公布日期 |
2003.03.13 |
申请号 |
US20010951535 |
申请日期 |
2001.09.14 |
申请人 |
DEGUSA HULS AKTIENGESELSCHAFT |
发明人 |
ZIEGLER PETRA;EGGELING LOTHAR;SAHM HERMANN;THIERBACH GEORG |
分类号 |
C12N15/09;C07K14/34;C12N1/21;C12N15/01;C12N15/31;C12N15/77;C12P13/08;C12R1/15;(IPC1-7):C12P13/04;C07H21/04;C12N9/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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