SYSTEMS AND METHODS FOR REVERSIBLY BLOCKING NERVE ACTIVITY
摘要
A system and method for blocking nerve impulses using an implanted electrode located on or around a nerve. A specific waveform (34) is used that causes the nerve membrane to become incapable of transmitting an action potential. The waveform has a first phase (36) that produces subthreshold depolarization of the nerve membrane, and a second phase (38) having a shorter duration. The membrane is only affected underneath the electrode, and the effect is immediately and completely reversible. The waveform has a low amplitude and can be charge balanced, with a high likelihood of being safe to the nerve for chronic condition. It is possible to selectively block larger (motor) nerve fibers within a mixed nerve, while allowing sensory information to travel through unaffected nerve fibers.
申请公布号
WO02065896(A3)
申请公布日期
2003.03.13
申请号
WO2002US04887
申请日期
2002.02.20
申请人
CASE WESTERN RESERVE UNIVERSITY;KILGORE, KEVIN, L.;GRILL, WARREN, M.;MCINTYRE, CAMERON, C.;MORTIMER, JOHN, THOMAS
发明人
KILGORE, KEVIN, L.;GRILL, WARREN, M.;MCINTYRE, CAMERON, C.;MORTIMER, JOHN, THOMAS