发明名称 |
IMPROVED COMPOSITIONS AND METHODS FOR PRODUCING ANTIBODIES TO LOW MOLECULAR WEIGHT ANALYTES |
摘要 |
Improved immunogenic compositions and methods for producing antibodies to low molecular weight analytes are presented. In one series of embodiments particularly useful for production of antibodies having specificity for metal ions, nonimmunogenic polymers having natural metal ion-binding activity, typically alginates, are used, after contact with metal ions, as an immunogenic composition. In another series of embodiments, immunogens are enmeshed in a crosslinked protein network to create a potent immunogenic composition. In the latter embodiments, gelatins of cold-water fish prove surprinsingly efficacious. |
申请公布号 |
WO0248675(A3) |
申请公布日期 |
2003.03.13 |
申请号 |
WO2001US47544 |
申请日期 |
2001.12.12 |
申请人 |
TRANSDERM TECHNOLOGIES, LLC |
发明人 |
SARAVIS, CALVIN, A.;COOK, RICHARD, B. |
分类号 |
A61K39/00;C07K16/44 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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