ELECTROCHEMICAL DNA-SENSOR, METHOD FOR PRODUCING AND OPERATING A DNA-SENSOR OF THIS TYPE

摘要

DNA-sensors consisting of electrode arrays with interdigital structures are known. According to the invention, the interdigital structure (2, 3) has additional reaction surfaces (5) for attaching thiols (100). To produce a DNA-sensor of this type, an additional non-precious metal, e.g. copper, is first deposited on the electrode surfaces and a solution containing thiols is applied to the sensor array. The thiols attach themselves to the free surfaces and the metal and thiols attached thereto are subsequently removed using diluted sulphuric acid. During the operation of a sensor of this type, markers (300) are attached to the surfaces covered by the thiols.