ATTENUATED HIV STRAINS AND USE THEREOF

摘要

The invention provides an isolated human immunodeficiency virus, comprising at least one non revertant mutation capable of delaying or diminishing the pathological behavior of said immunodeficiency virus when compared to a human immunodeficiency virus not having at least one such a mutation. A virus of the invention can be used for the preparation of a vaccine for Aids. Said virus can also be used for diagnostic assays in HIV-infected patients.