A NON-STEROIDAL ANTI-INFLAMMATORY DRUG ACTIVATED GENE WITH ANTI-TUMORIGENIC PROPERTIES
摘要
The present invention provides methods and compositions for drug screens to identify and characterize agents that are agonistic or antagonistic to activation of the promoter region of the NAG-1 gene. Activation of the NAG-1 gene is associated with the apoptotic elimination of cancer cells both in vitro and in vivo. The invention also provides novel promoter region sequences of the NAG-1 gene.
申请公布号
WO0220759(A3)
申请公布日期
2003.03.13
申请号
WO2001US27544
申请日期
2001.09.06
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;ELING, THOMAS, E.;BAEK, SEUNG, JOON