发明名称 |
SOLUBLE T CELL RECEPTOR |
摘要 |
The present invention provides a soluble T cell receptor (sTCR), which comprises (i) all for part of a TCR alpha chain, except the transmembrane domain thereof, and (ii) all or part of a TCR beta chain, except the transmembrane domain thereof. (i) and (ii) each comprise a functional variable domain and at least a part of the constant domain of the TCR chain, and are linked by a disulphide bond between constant domain residues which is not present in native TCR. |
申请公布号 |
WO03020763(A2) |
申请公布日期 |
2003.03.13 |
申请号 |
WO2002GB03986 |
申请日期 |
2002.08.30 |
申请人 |
AVIDEX LIMITED;JAKOBSEN, BENT, KARSTEN;GLICK, MEIR |
发明人 |
JAKOBSEN, BENT, KARSTEN;GLICK, MEIR |
分类号 |
G01N33/53;A61K9/127;A61K38/00;A61K47/48;A61K48/00;A61P3/10;A61P31/12;A61P31/18;A61P35/00;A61P37/02;C07K14/725;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;G01N33/566 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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