发明名称 |
Method of treating wounds by enhancing expression of procollagen |
摘要 |
The present invention provides methods for identifying compounds useful for the treatment of wounds by determining whether the compound increases the expression of type I procollagen and/or type III procollagen by human fibroblasts cultured in the presence of collagen. The present invention also provides methods for treating wounds by applying to the wound and/or surrounding tissue a therapeutically effective amount of anabolic steroid in a pharmaceutically acceptable formulation, wherein the steroid is not administered systemically to a patient. The present invention also provides compositions comprising at least one anabolic steroid in an amount effective to promote collagen production in at the site of a wound, wherein the composition is a pharmaceutically acceptable formulation suitable for local administration.
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申请公布号 |
US2003049716(A1) |
申请公布日期 |
2003.03.13 |
申请号 |
US20020058066 |
申请日期 |
2002.01.29 |
申请人 |
M.D NORMAN BARTON;M.D. THEODORE KRAMER |
发明人 |
M.D NORMAN BARTON;M.D. THEODORE KRAMER |
分类号 |
A61K31/00;A61K31/56;(IPC1-7):C12Q1/26 |
主分类号 |
A61K31/00 |
代理机构 |
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地址 |
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