| 摘要 |
<p>The present invention relates to a method for identifying a substance capable of modulating the number of nucleotide repeats in a cell displaying expanded nucleotide repeat instability. The present invention further provides the use of a substance or substances identified by the assay of the present invention in the treatment of inherited human or animal disease characterised by nucleotide repeat expansion, for example Huntington's disease and the like as well as cells and/or cell lines, which may be used in the method.</p> |
