| 发明名称 |
Control of lymphocyte localization by LEEP-CAM activity |
| 摘要 |
A novel cell surface glycoprotein, LEEP-CAM, is disclosed. This invention further provides methods for treating inflammatory disorders in mammals through the administration of compositions which are modulators of LEEP-CAM activity. Antibodies are also disclosed which prevent LEEP-CAM-mediated migration of lymphocytes into epithelial layers of cells.
|
| 申请公布号 |
US2003049259(A1) |
申请公布日期 |
2003.03.13 |
| 申请号 |
US20020054714 |
申请日期 |
2002.01.22 |
| 申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
BRENNER MICHAEL B.;PARKER CHRISTINA M.;SCHON MICHAEL P. |
| 分类号 |
A61K38/00;A61K39/00;A61P29/00;C07K14/705;C07K16/28;(IPC1-7):A61K39/395;A61K31/00;C07K16/40 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
