| 发明名称 |
INDOLE DERIVATIVES WITH VASCULAR DAMAGING ACTIVITY |
| 摘要 |
The invention provides a compound of Formula (I). Wherein R1, R2, R3, R10 and R11 have the meanings given in the description. Such compounds are predicted to cause the selective destruction of tumour vasculature. They may therefore be used to inhibit and/or reverse, and/or alleviate symptoms of angiogenesis and/or any disease state associated with angiogenesis. |
| 申请公布号 |
EP1289952(A1) |
申请公布日期 |
2003.03.12 |
| 申请号 |
EP20010931944 |
申请日期 |
2001.05.25 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
ARNOULD, JEAN-CLAUDE;BIRD, THOMAS, GEOFFREY;BOYLE, FRANCIS, THOMAS;BLAKEY, DAVID, CHARLES |
| 分类号 |
A61K31/404;A61K31/40;A61K31/496;A61K31/661;A61P3/10;A61P9/00;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07D209/42;C07F9/12;C07F9/572 |
主分类号 |
A61K31/404 |
| 代理机构 |
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