| 摘要 |
PURPOSE: A process for selectively removing catechol from a mixture of 2,3-dihydro-2,2-dimethyl-7-benzofuranol(7-OH) and catechol is provided, thereby preparing high purity 7-OH without a neutralization process. CONSTITUTION: The process for selectively removing catechol from a mixture of 2,3-dihydro-2,2-dimethyl-7-benzofuranol(7-OH) and catechol comprises the steps of: dissolving the mixture of 2,3-dihydro-2,2-dimethyl-7-benzofuranol(7-OH) and catechol in organic solvent such as methyl isobutyl ketol(MIBK) and toluene; adding inorganic salts into the dissolved mixture in the amount of 1 to 2 equivalency per 1 equivalency of catechol; stirring the mixture at 50 to 150 deg.C to prepare a precipitate of catechol-inorganic salt complex of formula (III); filtering the precipitate and removing the organic solvent to obtain 2,3-dihydro-2,2-dimethyl-7-benzofuranol(7-OH); and adding 20 to 150 ml of water into the catechol-inorganic salt complex to recover catechol and inorganic salts, wherein the organic salt is MgCl2, MgBr2, Mg(OEt)2 and FeCl2.
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