发明名称 Pyridin-2-ylaminoalkyl carbonylglycyl-beta-alanine derivative, process of its preparation and use as well as pharmaceutical preparation in which the derivative is comprised
摘要 <p>The invention relates to compounds of the formula I R<1 >is H, A, Ar, Hal, -OH, -O-A, -CF3 or -OCF3; R<2 >and R<7 >are H or A; R<3 >is R<4>, R<5 >and R<6 >are in each case, independently of each other, H, A, Hal, -OH, -O-A, -CF3, -OCF3, -CN, -NH2, -A-NH2; A is C1-C6-alkyl; Ar is a substituent which is formed by an aromatic radical which is optionally substituted once, twice or three times by R<5 >and which has from 1 to 3 ring structures which are optionally fused with other ring structures to form a fused ring system; Het is a substituent which is formed by a heterocycle which has from 1 to 3 ring structures, with each ring structure being saturated, unsaturated or aromatic and being optionally fused with other ring structures to form a fused ring system, and the heterocycle possessing a total of from 1 to 4 N, O and/or S atoms in the ring structures and being optionally substituted by R<6>; Hal is F, Cl, Br or I; n is 2, 3, 4, 5 or 6 and to their use.</p>
申请公布号 CZ20023952(A3) 申请公布日期 2003.03.12
申请号 CZ20020003952 申请日期 2001.06.12
申请人 MERCK PATENT GMBH 发明人 HOLZEMANN GUNTER;GOODMAN SIMON
分类号 A61K38/00;A61P7/02;A61P9/10;A61P19/10;A61P29/00;A61P31/04;A61P35/00;C07K1/20;C07K5/023;C07K5/068;C07K5/072;(IPC1-7):C07K5/02;A61K38/06;C07K5/08 主分类号 A61K38/00
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