发明名称 METHOD OF DETECTING LUNG DISEASE
摘要 PROBLEM TO BE SOLVED: To provide lung diagnostic assays in general, and particularly provide a lung diagnostic assay in which lung mucus secretions are hydrated to facilitate collection thereof. SOLUTION: The pharmaceutical composition useful for promoting of the obtaining of a mucus sample from at least one lung of a subject comprising a compound represented by formula (I) [wherein X1 , X2 and X3 are each independently OH or SH; R1 is selected from a group consisting of O, imide, methylene and a dihalomethylene; R2 is H or Br] or its pharmaceutically acceptable salt in an amount effective to stimulate lung mucous secretions in at least one lung of the subject and/or stimulate cilia beat frequency in the lung.
申请公布号 JP2003073280(A) 申请公布日期 2003.03.12
申请号 JP20020227140 申请日期 2002.08.05
申请人 UNIV NORTH CAROLINA AT CHAPEL HILL:THE 发明人 BOUCHER JR RICHARD C
分类号 C07H19/10;A61B5/00;A61B10/00;A61K9/00;A61K31/495;A61K31/675;A61K31/7064;A61K33/14;A61K45/06;A61P11/10;C07G99/00;C07H19/04;C07H19/06;C08J11/08;C12Q1/00;C12Q1/48;G01N33/48;(IPC1-7):A61K31/706 主分类号 C07H19/10
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