| 摘要 |
A stabilised cosmetic material containing triple-encapsulated retinol. The retinol is stabilized firstly by addition into vesicles consisting of nonionic surface-active agent, an alkyl phosphate, cholesterol, cholesteryl ester and a polyhydric alcohol. The firstly stabilised retinol is subsequently inserted into sphingosomes consisting of lecithin, ceramide and an oily carrier. Finally the double-encapsulated retinol is inserted into lamellar liquid-crystal emulsifying base, thereby being triply encapsulated. The preferable nonionic surface-active agents are stearyl glucoside, glyceryl stearate, tocopheryl acetate and sorbitan stearate. Preferably, the oily carriers are paraffin or liquid paraffin, the alkyl phosphate is selected from mono-, di-, tri- and polyoxyethylene alkylphosphate and the polyhydric alcohol is glycerine. More preferably, the lamellar liquid-crystal emulsifying base comprises an anionic surface-active agent, a higher fatty alcohol, a higher fatty acid and ceramide. Even more preferably, the anionic surface-active agent is alkyl phosphate.
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