MALTO-OLIGOSACCHARIDE DERIVATIVES AND USE THEREOF

摘要

The present invention provides a substance which strongly inhibits human alpha -amylase and is effective for the prevention and treatment of hyperglycemia, for example, diabetes and the diseases caused thereby, and an alpha -amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia containing the said substance as active principle. Maltoligosaccharide derivatives represented by the following formula: <CHEM> (wherein n is an integer of 0 to 2; m is an integer of 0 to 2; and X represents a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts are provided, and they are contained as active principle to prepare an alpha -amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia such as diabetes. <IMAGE>