发明名称 Pharmaceutical compositions incorporating aryl substituted olefinic amine compounds
摘要 Patients susceptible to or suffering from central nervous system disorders (e.g., Alzheimer's disease, Parkinson's disease, Tourette's syndrome, attention deficit disorder or schizophrenia) are treated by administering an effective amount of an aryl substituted olefinic amine compound. Exemplary compounds include (E)-N-methyl-4-[3-(5-benzyloxypyridin)yl]-3-buten-1-amine, (E)-N-methyl-4-[3-(5-phenoxypyridin)yl]-3-buten-1-amine, (E)-N-methyl-4-[3-(5-isopropoxypyridin)yl]-3-buten-1-amine, (E)-N-methyl-4-[3-(5-methoxymethylpyridin)yl]-3-buten-1-amine, and (E)-N-methyl-4-[3-(5-phenylpyridin)yl]-3-buten-1-amine.
申请公布号 US6531606(B1) 申请公布日期 2003.03.11
申请号 US19970804250 申请日期 1997.02.21
申请人 TARGACEPT, INC. 发明人 DULL GARY MAURICE;CALDWELL WILLIAM SCOTT;DOBSON GRAYLAND PAGE;MILLER CRAIG HARRISON
分类号 C07D213/38;C07D213/61;C07D213/64;(IPC1-7):C07D211/72;C07D213/26;C07D239/00;A61K31/505 主分类号 C07D213/38
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