| 摘要 |
PURPOSE: Provided is a use of sphingoid base for inhibiting ceramidase activity to provide a composition which is capable of affecting the activity of ceramidases responsible for the unwanted hydrolysis of ceramides. CONSTITUTION: An active compound selected from the group of a sphingoid base, a derivative of a sphingoid base, a salt of a sphingoid base, a ceramide or a mixture of two or more of these compounds is characteristically used for manufacturing a composition for topical application for inhibiting ceramidase activity in and on the skin.
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