摘要 |
The invention relates to a method of identifying, screening or selecting a compound that binds to the transglycosylation site of a recombinant glycosyl transferase. The inventive method consists in: a) bringing the compound into contact with the recombinant protein before, after or at the same time as said recombinant protein is brought into contact with a transglycosylation activity inhibitor, said inhibitor being marked by a marker that generates a direct or indirect signal; b) examining the signal linked to said recombinant protein, the link between the compound and the transglycosylation site being deduced from the difference between the signal obtained in step (b) and the signal obtained in the absence of said compound.
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