发明名称 HELICOBACTER PYLORI VACCINATION
摘要 A sterile immunogenic preparation of three purified H.pylori antigens (CagA, VacA and NAP) adjuvanted with alum in an isotonic buffer solution for intramuscular injection. The antigens may be administered in conjunction wit h antibiotics and/or antisecretories. Urease breath testing, stool antigen testing, and/or immunological analysis may be used as correlate(s) of protection against H.pylori infection. Urea may be used to improve VacA solubility.
申请公布号 CA2458854(A1) 申请公布日期 2003.03.06
申请号 CA20022458854 申请日期 2002.09.02
申请人 CHIRON SRL 发明人 DEL GIUDICE, GIUSEPPE
分类号 A61M5/28;A61K9/08;A61K39/02;A61K39/05;A61K39/08;A61K39/085;A61K39/09;A61K39/095;A61K39/10;A61K39/102;A61K39/106;A61K39/116;A61K39/118;A61K39/12;A61K39/13;A61K39/145;A61K39/165;A61K39/205;A61K39/29;A61K39/39;A61K45/00;A61K47/04;A61K47/16;A61P1/04;A61P31/04;C12Q1/58;(IPC1-7):A61K39/106 主分类号 A61M5/28
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