发明名称 |
PLEIOTROPHIN GROWTH FACTOR RECEPTOR FOR THE TREATMENT OF PROLIFERATIVE, VASCULAR AND NEUROLOGICAL DISORDERS |
摘要 |
This invention relates to the discovery that pleiotrophin binds to and activates a pleiotrophin-receptor which is responsible for the events associated with pleiotrophin activity including tumorigenesis, cell proliferation, and cell invasion. By interfering with that association, the cascade of events associated with pleiotrophin activity can be prevented or reversed. Further, by evaluating the effect of different compounds and conditions on the interction, new drugs and treatments can be identified for use in preventing certains cancers and growth and developmental disorders. |
申请公布号 |
WO0196394(A3) |
申请公布日期 |
2003.03.06 |
申请号 |
WO2001US18938 |
申请日期 |
2001.06.14 |
申请人 |
GEORGETOWN UNIVERSITY MEDICAL CENTER;WELLSTEIN, ANTON |
发明人 |
WELLSTEIN, ANTON |
分类号 |
A61K38/00;A61K39/00;C07K14/475;C07K14/71 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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