DIFFERENTIATION OF NEURAL STEM CELLS AND THERAPEUTIC USE THEREOF

摘要

This invention relates to a method of selectively producing neural cells, including neurons or glial cells, in vitro orin vivo. Also provided are methods of treating or ameliorating neurodegenerative disease or medical conditions by producing neural cells. Thus, a combination of factors is used to achieve two steps: increasing the number of neural stem cells and instructing the neural stem cells to selectively become neurons or glial cel ls.