PROCESS FOR PURIFYING GLYCOPEPTIDE PHOSPHONATE DERIVATIVES

摘要

Disclosed are methods of purifying glycopeptides that are substituted with o ne or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting th e resin with an aqueous solution, and isolating the purified glycopeptide derivative.