DISPLACEMENT ASSAY FOR THE DETECTION OF NUCLEIC ACID OLIGOMER HYBRIDIZATION EVENTS

摘要

Disclosed is a method for the detection of nucleic acid oligomer hybridization events, comprising the following steps: provision of a modified surface, said modification consisting in the binding of at least one type of ligate-nucleic acid oligomer; provision of signal nucleic acid oligomer ligands; provision of a sample with nucleic acid oligomer ligands; a defined amount of signal nucleic acid oligomer ligands is brought into contact with the modified surface and the sample and the nucleci acid oligomer ligands are brought into contact with the modified surface; detection of the signal nucleic acid oligomer ligands and comparing the values obtained during detection of the signal nucleic acid oligomer ligands with reference values.