Cycloalkyl-substituted aminomethylpyrrolidine derivatives

摘要

This invention provides a quinolone derivative which exerts strong antibacterial action upon various bacteria and has high safety, and it relates to a compound having a structure of formula (I), its salts and hydrates thereof: äR<1> and R<2>: hydrogen, alkyl; n: 1 to 4; Q: following structure (Ia): ÄR<3>: alkyl, alkenyl, halogenoalkyl, cyclic alkyl, aryl, heteroaryl, alkoxyl, alkylamino; R<4>: hydrogen, alkylthio; R<5>: hydrogen, amino, hydroxyl, thiol, halogenomethyl, alkyl, alkenyl, alkynyl, alkoxyl; X<1>: halogen, hydrogen, A<1>: nitrogen, structure of formula (II): (X<2>: hydrogen, amino, halogen, cyano, halogenomethyl, halogenomethoxyl, alkyl, alkenyl, alkynyl, alkoxyl; R<4> and R<3> or X<2> and R<3> may together form a cyclic structure; Y: hydrogen, various ester forming groupsÜü.