SERINE PROTEASE INHIBITOR AND PROCESSES FOR THE PREPARATION THEREOF

摘要

A glycoprotein having an apparent molecular weight of about 54 kDa, which has serine protease inhibitor activity (a serpin-Iike molecule). The invention also relates to a process for preparing the same, methods as well as compositions for treating, preventing or alleviating the symptoms of disorders and diseases associated with an excess level of serine protease. Amongst these diseases are psoriasis, emphysema, pulmonary hypertension, liver fibrosis, anaemia, diseases characterized by tumor growth or invasion, as well as any disease involving mast cells.