发明名称 |
Surface modification for improving biocompatibility |
摘要 |
A therapeutic delivery system efficiently introduces biologically active molecules to mammalian cells without the use of synthetic polymers or biopolymer coatings. Surface modification of a metal support, such as a medical device, results in a single molecular layer that can fasten various molecules, thereby minimizing any cellular inflammatory response while enhancing biocompatibility.
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申请公布号 |
US2003044408(A1) |
申请公布日期 |
2003.03.06 |
申请号 |
US20020170411 |
申请日期 |
2002.06.14 |
申请人 |
THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
LEVY ROBERT J.;ALFERIEV IVAN;SONG CUNXIAN;FISHBEIN LLIA |
分类号 |
A61K38/00;A61K39/00;A61K47/48;A61K48/00;C12N15/87;(IPC1-7):A61K39/395;A61K38/40;A61K31/418;A61K38/17 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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