| 发明名称 |
Toll-like receptor 5 ligands and methods of use |
| 摘要 |
The invention provides an immunomodulatory flagellin peptide having at least about 10 amino acids of substantially the amino acid sequence GAVQNRFNSAIT, or a modification thereof, and having toll-like receptor 5 (TLR5) binding. Methods of inducing an immune response are also provided.
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| 申请公布号 |
US2003044429(A1) |
申请公布日期 |
2003.03.06 |
| 申请号 |
US20020125692 |
申请日期 |
2002.04.17 |
| 申请人 |
ADEREM ALAN;HAYASHI FUMITAKA;SMITH KELLY D.;UNDERHILL DAVID M.;OZINSKY ADRIAN |
发明人 |
ADEREM ALAN;HAYASHI FUMITAKA;SMITH KELLY D.;UNDERHILL DAVID M.;OZINSKY ADRIAN |
| 分类号 |
A61K39/00;C07K14/195;C07K14/255;C12N15/31;(IPC1-7):A61K48/00;A61K39/02;A61K31/715;C12N9/00 |
主分类号 |
A61K39/00 |
| 代理机构 |
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