发明名称 |
A SYSTEM FOR ANTIBODY EXPRESSION AND ASSEMBLY |
摘要 |
The present invention provides methods and compositions for expression and production of recombinant antibodies in a host cell system, such as prokaryotic and eukaryotic expression systems. Particularly contemplated are recombinant systems for temporally separated expression of light chain and heavy chain of antibodies. The antibody products including antibody fragment s can be used in various aspects of biological research, diagnosis and medical treatment |
申请公布号 |
CA2454731(A1) |
申请公布日期 |
2003.03.06 |
申请号 |
CA20022454731 |
申请日期 |
2002.08.26 |
申请人 |
GENENTECH, INC. |
发明人 |
SIMMONS, LAURA C.;ANDERSEN, DANA C. |
分类号 |
C12N15/09;C07K16/00;C07K16/28;C07K16/36;C12N1/21;C12N15/13;C12P21/02;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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