发明名称 |
PHENYLPYRIDINE DERIVATIVE |
摘要 |
PROBLEM TO BE SOLVED: To provide a phenylpyridine derivative usable for prophylaxis and treatment of respiratory diseases associated with phosphodiesterase 4, especially bronchial asthma, chronic obstructive lung diseases, etc. SOLUTION: This phenylpyridine derivative or its salt respectively has a phenyl group which may be substituted with an alkoxy group, etc., in the 6-position and an N-substituted carbamoyl group or a nitrogen-containing heterocyclic ring-carbonyl group bound with nitrogen atom in the 2-position. Furthermore, the phenylpyridine derivative or its salt has a potent and selective inhibitory activity on the phosphodiesterase 4 and is pharmaceutically useful.
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申请公布号 |
JP2003064057(A) |
申请公布日期 |
2003.03.05 |
申请号 |
JP20020172377 |
申请日期 |
2002.06.13 |
申请人 |
YAMANOUCHI PHARMACEUT CO LTD |
发明人 |
IWATA MASAHIRO;KONO NORIYUKI;KAIZAWA HIROYUKI;TAKUWA TOMOFUMI;TSUKAMOTO KAZUNARI;SEO TATSUSHI;YAHIRO KIYOSHI;KOBAYASHI MIKI;TAKEUCHI MAKOTO |
分类号 |
C07D213/81;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/496;A61K31/497;A61K31/5377;A61K31/541;A61K31/55;A61P11/00;A61P11/06;A61P43/00;C07D213/89;C07D401/12;C07D401/14;C07D405/04;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D471/04;C07D471/18;(IPC1-7):C07D213/81;A61K31/454;A61K31/470;A61K31/537 |
主分类号 |
C07D213/81 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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