发明名称 |
PLATELET GPIIIa P1A1 AND P1A2 EPITOPES, THEIR PREPARATION AND USE |
摘要 |
<p>Polypeptides and fusion polypeptides that immunologically mimic the native PlA1 and PlA2 determinants of platelet protein GPIIIa are disclosed. Also disclosed are DNA segments and recombinant DNA molecules that encode those polypeptides and fusion polypeptides and methods for expressing and using those determinants. Antibodies that immunoreact with one determinant or the other, but not both are also disclosed, as are methods of preparing and using those antibodies.</p> |
申请公布号 |
EP0625157(B1) |
申请公布日期 |
2003.03.05 |
申请号 |
EP19930900656 |
申请日期 |
1992.11.24 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
BOWDITCH, RONALD, D.;MCMILLAN, ROBERT;GINSBERG, MARK, H. |
分类号 |
G01N33/53;C07K14/47;C07K14/705;C07K16/00;C07K16/18;C07K16/28;C07K16/34;C07K19/00;C12N15/12;C12Q1/68;(IPC1-7):C12N15/12;C12N15/62;C12N15/70;G01N33/68;G01N33/543;G01N33/577;G01N33/80;G01N33/532 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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