| 发明名称 |
Cyclin-selective ubiquitin carrier polypeptides |
| 摘要 |
Disclosed are novel human and clam ubiquitin carrier polypeptides involved in the ubiquitination of cyclins A and/or B. Also disclosed are inhibitors of such polypeptides, nucleic acids encoding such polypeptides and inhibitors, antibodies specific for such polypeptides, and methods of their use.
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| 申请公布号 |
US6528633(B2) |
申请公布日期 |
2003.03.04 |
| 申请号 |
US20010772156 |
申请日期 |
2001.01.29 |
| 申请人 |
PRESIDENT AND FELLOWS OF HAVARD COLLEGE;RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES |
发明人 |
RUDERMAN JOAN V.;HERSHKO AVRAM;KIRSCHNER MARC W.;TOWNSLEY FIONA;ARISTARKOV ALEXANDER;EYTAN ESTHER;YU HONGTAO |
| 分类号 |
C12N15/09;A61K38/00;A61K45/00;A61K48/00;C07K14/435;C07K14/47;C12N9/00;(IPC1-7):C07H21/04 |
主分类号 |
C12N15/09 |
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