COMPOSITION OF TREATING DIARRHEA IN MAMMALS CONTAINING BUFORIN II

摘要

PURPOSE: A composition of treating diarrhea in mammals containing buforin II which is separated a Korean toad and has an antimicrobial effect against cause bacteria of diarrhea is provided. The composition exhibits high susceptibility against cause bacteria of diarrhea and kills cause bacteria by inhibition of intracellular physiological action of the diarrhea cause bacteria. CONSTITUTION: The composition for prevention and treatment of diarrhea contains 0.01 to 20% by weight of buforin II, based on the total weight of the composition. The composition is powder, a drug, a tablet or injectable formulation and can be also used as a vaccine preparation, a feed additive or a beverage additive. Daily dose of between about 400μg to 4mg/day is sufficient to treat diarrhea in mammals.