发明名称 AMIDE AND UREA DERIVATIVES AS 5-HT REUPTAKE INHIBITORS AND AS 5-HT1B/1D LIGANDS
摘要 <p>Amide and urea derivatives of the formula Iin which R1, n, Y, q, Z, r and R2 have the meanings indicated in Claim 1, are potent 5-HT1B/1D antagonists and exhibit 5-HT reuptake-inhibiting actions and are suitable for the treatment and prophylaxis of anxiety states, depressions, schizophrenia, compulsive ideas, tardive dyskinesias, learning disorders, age-dependent memory disorders, for positively affecting obsessive-compulsive behaviour (OCD), and also for the treatment and for the control of the sequelae of cerebral infarcts such as stroke and cerebral ischaemias.</p>
申请公布号 SI1140898(T1) 申请公布日期 2003.02.28
申请号 SI19980030281T 申请日期 1998.12.22
申请人 MERCK PATENT GMBH 发明人 MATZEN LISA;BOETTCHER HENNING;VAN AMSTERDAM CHRISTOPH;BARTOSZYK GERD;GREINER HARTMUT;HARTING JUERGEN;RAUTENBERG WILFRIED
分类号 C07D491/107;A61K31/40;A61K31/454;A61K31/496;A61P1/06;A61P9/12;A61P15/10;A61P15/12;A61P15/14;A61P25/06;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P43/00;C07D209/14;C07D209/16;C07D401/04;C07D401/06;C07D401/14;C07D403/12;(IPC1-7):C07D401/04 主分类号 C07D491/107
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