发明名称 Branched alkyl pyrrolidine-3-carboxylic acids useful in protective action against cardiazole cramp and cerebral conditions such as epilepsy, hypokinesia and cranial traumas
摘要 Branched alkyl pyrrolidines of formula (I) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed. R1 is H or a straight or a branched C1-5alkyl; R2 is a straight or a branched C1-5alkyl; R1 and R2 togather form a carbocyclic ring having 3 to 7 atoms.
申请公布号 NZ510145(A) 申请公布日期 2003.02.28
申请号 NZ19990510145 申请日期 1999.08.11
申请人 WARNER-LAMBERT COMPANY 发明人 BRYANS, JUSTIN STEPHEN;EKHATO, IHOEZO VICTOR;HORWELL, DAVID CHRISTOPHER;LING, RONG;RECEVEUR, JEAN-MARIE;WUSTROW, DAVID JUERGEN
分类号 A61K31/40;A61P1/00;A61P19/02;A61P25/00;A61P25/08;A61P25/10;A61P25/14;A61P25/22;A61P25/24;A61P29/00;A61P29/02;C07D207/16;(IPC1-7):C07D207/16 主分类号 A61K31/40
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