发明名称 |
Branched alkyl pyrrolidine-3-carboxylic acids useful in protective action against cardiazole cramp and cerebral conditions such as epilepsy, hypokinesia and cranial traumas |
摘要 |
Branched alkyl pyrrolidines of formula (I) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed. R1 is H or a straight or a branched C1-5alkyl; R2 is a straight or a branched C1-5alkyl; R1 and R2 togather form a carbocyclic ring having 3 to 7 atoms.
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申请公布号 |
NZ510145(A) |
申请公布日期 |
2003.02.28 |
申请号 |
NZ19990510145 |
申请日期 |
1999.08.11 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BRYANS, JUSTIN STEPHEN;EKHATO, IHOEZO VICTOR;HORWELL, DAVID CHRISTOPHER;LING, RONG;RECEVEUR, JEAN-MARIE;WUSTROW, DAVID JUERGEN |
分类号 |
A61K31/40;A61P1/00;A61P19/02;A61P25/00;A61P25/08;A61P25/10;A61P25/14;A61P25/22;A61P25/24;A61P29/00;A61P29/02;C07D207/16;(IPC1-7):C07D207/16 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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