发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE |
摘要 |
<p>Compositions which increase the bioavailability of proteinase inhibitors are disclosed. Compositions which include a pharmaceutically acceptable carrier comprising monoglycerides of medium chain-fatty acids are preferred. Preferred medium chain fatty acid glycerides include monoglycerides of saturated C6 to C12 fatty acids, preferably C8 to C10 fatty acids The pharmaceutically acceptable carrier preferably has an acid value of less than or equal to about 2.5. Preferably, the ratio of monoglycerides of medium chain fatty acid to the proteinase inhibitor is about at least 1.5.</p> |
申请公布号 |
SI831826(T1) |
申请公布日期 |
2003.02.28 |
申请号 |
SI19960030535T |
申请日期 |
1996.06.04 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BAILEY CAROLE ANNE;FERDINANDO JOSEPHINE CHRISTINE;SHAH NAVNIT |
分类号 |
A61K9/48;A61K31/47;A61K31/4725;A61K47/14;(IPC1-7):A61K31/47 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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