发明名称 SHORTLY ACTING DIHYDROPYRIDINES
摘要 PCT No. PCT/SE94/01031 Sec. 371 Date Dec. 14, 1994 Sec. 102(e) Date Dec. 14, 1994 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/12578 PCT Pub. Date May 11, 1995Compounds of the general formula <IMAGE> I wherein R1 and R2 are independently selected from the group consisting of hydrogen, chloro, bromo, nitro, cyano, trifluoromethyl, and R3 and R4 are independently selected from straight or branched lower (1-5 carbon atoms) alkyl groups, and including all optical isomers, provided that when R3 is methyl and R4 is tert.-butyl, then R1/R2 are not hydrogen/hydrogen, hydrogen/2'-trifluormethyl, 2'-chloro/3'-chloro, and when R3 is methyl and R1/R2 is hydrogen/3'-nitro, then R4 are not methyl, ethyl, propyl, iso-propyl, tert.-butyl, processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in lowering the blood pressure.
申请公布号 PL185099(B1) 申请公布日期 2003.02.28
申请号 PL19940314128 申请日期 1994.11.03
申请人 ASTRA AB 发明人 ANDERSSON KJELL H.;NORDLANDER MARGARETA;WESTERLUND ROLF C.
分类号 A61K31/44;A61K31/4422;A61P9/12;C07D211/90 主分类号 A61K31/44
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