发明名称 RAPID PREPARATION OF STEM CELL MATRICES FOR USE IN TISSUE AND ORGAN TREATMENT AND REPAIR
摘要 The present invention describes a rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the prestn invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may behomogeneous, heterrogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions as described provide point of service utility for the practitioner, wherin the stem cells and matrix can be combined not long before use, therby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
申请公布号 WO02067867(A3) 申请公布日期 2003.02.27
申请号 WO2002US06125 申请日期 2002.02.22
申请人 THE UNIVERSITY OF PITTSBURGH 发明人 CHANCELLOR, MICHAEL, B,;HUARD, JOHNNY;CAPELLI, CHRISTOPHER;CHUNG, STEVE;SACKS, MICHAEL, S.
分类号 C12N11/02;A61K35/12;A61L27/00;A61L27/38;C12N5/00;C12N5/077 主分类号 C12N11/02
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