ANTIBACTERIAL OXAZOLIDINONES WITH A CYCLIC SULPHILIMINE OR SULPHOXIMINE

摘要

Compounds of formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, wherein, for example; T is selected, for example, from a group of formula (TA1) or (TA2), wherein, for example, X>1m< is O= and X>2m< is R>2s<-(E)>ms<-N-; wherein E is an electron withdrawing group, for example, -SO>2<- or -CO-; and, for example, R>2s< is hydrogen or (1-6C)alkyl; and, for example, HET(AR) is a 5 or 6 membered aromatic or heteroaromatic ring; and Y is NH and , for example, Z is hydrogen or -COR5 or CSR5, wherein R5 is, for example (1-6C)alkyl; are useful as pharmaceutical agents; and processes for their manufacture and pharmaceutical compositions containing them are described.