发明名称 USE OF alpha CP1, alpha CP2, AND HUR FOR MODULATING GENE EXPRESSION AND INDUCING ANGIOGENESIS
摘要 The present invention describes methods for modulating gene expression, stabilizing VEGF mRNAs, for inducing angiogenesis, for treating various mammalian diseases including coronary and cardiac diseases and for identifying modulators of gene expression by using human proteins called alpha CP1, alpha CP2 and HuR. The invention also describes mRNA stabilizing elements and consensus sequences involved in binding of alpha CP1, alpha CP2 and HuR proteins to mRNAs.
申请公布号 WO03016343(A2) 申请公布日期 2003.02.27
申请号 WO2002CA01275 申请日期 2002.08.16
申请人 ANGIOGENE INC.;GUY, LOUIS-GEORGES 发明人 GUY, LOUIS-GEORGES
分类号 C07K14/47;C12N15/63 主分类号 C07K14/47
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