发明名称 |
COMPOUNDS CAPABLE OF AFFECTING DIFFERENTIATION, PROLIFERATION, REGENERATION, PLASTICITY AND SURVIVAL OF CELLS |
摘要 |
The present invention relates to a compound comprising the third Immunoglobulin (Ig3) module, and/or the fourth Immunoglobulin (Ig4) module, and/or the fifth Immunoglobulin (Ig5) module, and/or the first Fibronectin III (Fn3, 1) module, and/or the second Fibronectin III (Fn3, 2) module of neural cell adhesion molecule (NCAM), or a fragment, or a variant thereof, capable of interacting with a Fibroblast Growth Factor (FGF) receptor and/or Adenosine-Tri-Phosphate (ATP) and/or L1, and thereby the compounds are capable of inducing differentiation, modulating proliferation, stimulate regeneration, neuronal plasticity and/or survival of cells. Further, the present invention relates to a pharmaceutical composition comprising said compound, a process of producing a pharmaceutical composition and the use of said compound. |
申请公布号 |
WO03016351(A2) |
申请公布日期 |
2003.02.27 |
申请号 |
WO2002DK00541 |
申请日期 |
2002.08.19 |
申请人 |
ENKAM PHARMACEUTICALS A/S;KISELYOV, VLADISLAV, V.;SKLADCHIKOVA, GALINA;BEREZIN, VLADIMIR;BOCK, ELISABETH |
发明人 |
KISELYOV, VLADISLAV, V.;SKLADCHIKOVA, GALINA;BEREZIN, VLADIMIR;BOCK, ELISABETH |
分类号 |
A61K38/00;A61P1/18;A61P3/10;A61P9/10;A61P13/12;A61P17/02;A61P21/00;A61P21/04;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P35/00;C07K7/06;C07K7/08;C07K14/705;C07K14/78 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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