| 发明名称 |
SYNTHESIS AND USE OF REAGENTS FOR IMPROVED DNA LIPOFECTION AND/OR SLOW RELEASE PRODRUG AND DRUG THERAPIES |
| 摘要 |
The invention relates to compositions and methods for a one-step synthetic technique for making cationic steroid or cationic drug molecules for use as delivery vehicles. The invention further relates to methods for using cationic steroid molecules in lipofection or transfection, delivery of drugs, and for treatment of inflamrnation and other diseases and disorders. The invention also relates to cationic steroid prodrugs and cationic prodrugs and to methods of modifying drugs.
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| 申请公布号 |
WO03015757(A1) |
申请公布日期 |
2003.02.27 |
| 申请号 |
WO2002US26152 |
申请日期 |
2002.08.15 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;DIAMOND, SCOTT, L.;GRUNEICH, JEFFREY |
发明人 |
DIAMOND, SCOTT, L.;GRUNEICH, JEFFREY |
| 分类号 |
A61K47/48;A61K9/127;A61K9/22;A61K31/366;A61K31/4439;A61K31/56;A61K38/00;A61K38/22;A61K47/20;A61K47/24;A61K47/28;A61K47/34;A61K47/42;A61K47/46;A61K48/00;A61P1/04;A61P1/14;A61P3/04;A61P3/06;A61P3/10;A61P7/04;A61P7/06;A61P9/00;A61P9/10;A61P9/12;A61P11/02;A61P11/06;A61P15/08;A61P15/10;A61P17/04;A61P17/06;A61P19/02;A61P19/10;A61P25/04;A61P25/08;A61P25/14;A61P25/22;A61P25/24;A61P29/00;A61P31/04;A61P31/14;A61P31/20;A61P35/00;A61P35/04;A61P37/06;A61P37/08;A61P43/00;C12N15/88;(IPC1-7):A61K9/22;A01N37/18;A01N43/04;C12N15/87 |
主分类号 |
A61K47/48 |
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