The present invention provides novel Beta-lactam antibiotic-polysaccharide complexes having a lower dose of active moiety resulting in equal pharmacological and microbiological response compared to respective parent drugs, leading to lesser toxicity and reduced cost of treatment for the patients and also, the invention provides a process for the production of novel compositions containing Beta-lactam antibiotics, said process comprising the steps of reacting Beta-lactam ring containing antibiotics with polysaccharides in the presence of a solvent, and lyophilisation of the complex under vacuum.
申请公布号
WO0230469(A3)
申请公布日期
2003.02.27
申请号
WO2001IN00179
申请日期
2001.10.11
申请人
ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED;CHAKRABARTI, PRASANTA, KUMAR;RAO, CANAKAPALLI, BHAKTAVATSALA