摘要 |
Compounds of general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents._In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3', 5' -monophosphate specific phosphodiesterase (cGMP-specific PDE), in particular PDE5, and have utilisty in a variety of therapeutic areas wherein such inhibition is considered beneficial, including the treatment of cardiovascular disorders and erectile dysfunction. |
申请人 |
LILLY ICOS LLC;ORME, MARK, W.;SAWYER, JASON, SCOTT;DAUGAN, ALAIN, CLAUDE-MARIE;GOSIMINI, ROMAIN, LUC, MARIE;SCHULTZE, LISA, M. |
发明人 |
ORME, MARK, W.;SAWYER, JASON, SCOTT;DAUGAN, ALAIN, CLAUDE-MARIE;GOSIMINI, ROMAIN, LUC, MARIE;SCHULTZE, LISA, M. |