发明名称 CONDENSED PYRIDOINDOLE DERIVATIVES
摘要 Compounds of general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents._In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3', 5' -monophosphate specific phosphodiesterase (cGMP-specific PDE), in particular PDE5, and have utilisty in a variety of therapeutic areas wherein such inhibition is considered beneficial, including the treatment of cardiovascular disorders and erectile dysfunction.
申请公布号 WO0228865(A3) 申请公布日期 2003.02.27
申请号 WO2001US42175 申请日期 2001.09.17
申请人 LILLY ICOS LLC;ORME, MARK, W.;SAWYER, JASON, SCOTT;DAUGAN, ALAIN, CLAUDE-MARIE;GOSIMINI, ROMAIN, LUC, MARIE;SCHULTZE, LISA, M. 发明人 ORME, MARK, W.;SAWYER, JASON, SCOTT;DAUGAN, ALAIN, CLAUDE-MARIE;GOSIMINI, ROMAIN, LUC, MARIE;SCHULTZE, LISA, M.
分类号 A61K31/437;A61P1/00;A61P1/04;A61P7/04;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P13/08;A61P13/12;A61P15/06;A61P15/10;A61P19/10;A61P25/26;A61P27/06;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C07D471/14;C07D498/04;C07D498/14;C07D513/04;C07D513/14;C07D515/14 主分类号 A61K31/437
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