| 摘要 |
<p>Polynucleotides comprising molecular interaction sites of RNase P RNA that have particular secondary structure are provided. Methods of using such polynucleotides to screen, virtually or actually, combinatorial libraries of compounds that bind thereto are also provided. Method of modulating the activity of RNase P RNA by contacting RNase P RNA or prokaryotic cells containing the same with a compound identified by such virtual or actual screening are also provided.</p> |
