| 摘要 |
<p>Disclosed are mutants of protein kinase B/Akt which can be crystallised in an enzymaticallyactive conformation, crystals of these mutants and X-ray coordinate data for the crystals.Also disclosed are methods of using the coordinate data provided for identification ofmodulators of protein kinase activity and for structural analysis of other proteinkinases, in particular AGC kinases.</p> |
