发明名称 COMPOSITION OF PERFLUOROCARBON BLOOD SUBSTITUTE BASED ON EMULSION OF PERFLUOROORGANIC COMPOUNDS FOR MEDICAL-BIOLOGICAL AIMS
摘要 FIELD: medicine, biology. SUBSTANCE: invention relates to composition of perfluorocarbon blood substitute comprising of 2 perfluoroorganic compounds: perfluorodecaline and perfluoromethylcyclohexylpiperidine taken in the ratio 2: 1 and emulsified with proxanol-268 containing electrolyte solution in the concentration of perfluorocarbons in emulsion from 20% to 30% and concentration of proxanol in emulsion from 0.2% to 6% and no containing large-dispersed particles with diameter above 0.2 mcm, in average size of particles 0.03-0.05 mcm that can be sterilized by method of sterilizing filtration. Invention provides preparing blood substitute compositions with improved medical-biological and physical-chemical indices. Invention is designated for application of perfluorocarbon compositions as artificial blood. EFFECT: improved quality and properties of composition. 3 cl, 1 tbl, 4 ex
申请公布号 RU2199311(C2) 申请公布日期 2003.02.27
申请号 RU20010111373 申请日期 2001.04.26
申请人 VOROB'EV SERGEJ IVANOVICH 发明人 VOROB'EV S.I.
分类号 A61K9/107;A61K31/02;(IPC1-7):A61K9/107 主分类号 A61K9/107
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