Methods of screening for antimicrobial compounds

摘要

A method and assay for screening for antimicrobial compound comprises contacting bacteria having a detectable concentration with a target compound and determining the effect of the target compound on the concentration of the bacteria. The effect of the compound is determined by measuring the concentration of the bacteria at a plurality of times after the bacteria is contacted with the candidate compound. The method incorporates an assay, such as an optical density assay, luciferase-based assay, or kinetic assay.