摘要 |
The present invention provides compounds comprising a bicyclic aryl moiety, such as 2H-phthalazin-1-one or derivatives thereof, compositions comprising the same, and methods for producing and using the same. In particular, the present invention provides compounds of the formula: (I) or a pharmaceutical ly acceptable salt, a hydrate, a solvate, or a prodrug thereof; where Q1, Q2 an d Y are those defined herein.
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申请人 |
ICOS CORPORATION |
发明人 |
DEMAGGIO, ANTHONY J.;HUANG, DANWEN;BERTINO, JAIMIE A.;SONG, REN HUA;GOLDMAN, PHYLLIS;MOREE, WILNA J.;CHRISTENSON, ERIK;ZHICHKIN, PAVEL E.;FOWLER, KERRY W.;BEATON, GRAHAM;HERENDEEN, DAN;RUETER, JAIMIE K.;DAHL, RUSSELL S.;MCELLIGOTT, DAVID L.;REISCH, HELGE A.;JIANG, QIN;BOURDON, LISA H.;FAIRFAX, DAVID J. |