发明名称 |
USE OF BIBN4096 IN COMBINATION WITH OTHER ANTIMIGRAINE DRUGSFOR THE TREATMENT OF MIGRAINE |
摘要 |
The present invention relates to a method of treatment or prevention of headache, migraine or cluster headaches, which method comprises co- administration of a therapeutically effective amount of the compound A = 1-[ N2- [3,5-Dibromo-N-[[4-(3,4-dihydro-2(1 H)-oxochinazolin-3-yl)-1-piperidinyl]- carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine [BIBN4096BS] or a physiologically acceptable salt thereof and a therapeutically effective amou nt of a second active antimigraine drug, particularly sumatriptan, zolmitriptan or dihydroergotamin or a physiologically acceptable salt thereof, as well as to the corresponding pharmaceutical compositions and the preparation thereof .
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申请公布号 |
CA2454083(A1) |
申请公布日期 |
2003.02.27 |
申请号 |
CA20022454083 |
申请日期 |
2002.08.10 |
申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
EBERLEIN, WOLFGANG;RUDOLF, KLAUS;DOODS, HENRI |
分类号 |
A61K45/00;A61K31/404;A61K31/4045;A61K31/4196;A61K31/422;A61K31/454;A61K31/48;A61K31/517;A61K31/56;A61P1/08;A61P1/14;A61P3/14;A61P25/00;A61P25/02;A61P25/06;A61P25/08;A61P25/26;A61P29/00;A61P37/08;A61P43/00;(IPC1-7):A61K31/517 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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